paclitaxel side chain no.4

Name	N-benzoyl-(2R,3S)-3-phenylisoserine methyl ester
Synonyms	PACLITAXE SIDE CHIAN 4 PACLITAXEL SIDE CHAIN 4 paclitaxel side chain no.4 PACLITAXEL SIDE CHAIN NO 4 C-13 SIDE CHAIN FOR PACLITAXEL II (2R,3S)-3-phenylisoserine methyleste N-Benzoyl-3-Phenyl isoserine methyl ester (2R,3S)-N-benzoyl-3-PhenylisoserineMethylEster N-benzoyl-(2R,3S)-3-phenylisoserine methyl ester methyl (2R,3S)-3-benzamido-2-hydro-3-phenylpropionate methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropionate (2R,3S)-1-Benzoyl-2-Hydroxy-3-Aminophenylpionic Acid Ester (2R,3S)-1-benzoyl-2-hydroxy-3-aminophenylpionic acid ester Methyl(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate Methyl(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoale METHYL (2R,3S)-3-(BENZOYLAMINO)-2-HYDROXY-3-PHENYLPROPANOATE methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
CAS	32981-85-4
EINECS	608-809-6
InChI	InChI=1/C17H17NO4/c1-22-17(21)15(19)14(12-8-4-2-5-9-12)18-16(20)13-10-6-3-7-11-13/h2-11,14-15,19H,1H3,(H,18,20)/t14-,15+/m0/s1

Molecular Formula	C17H17NO4
Molar Mass	299.32
Density	1.236±0.06 g/cm3(Predicted)
Melting Point	178-183℃
Boling Point	540.3±50.0 °C(Predicted)
Flash Point	280.6°C
Solubility	DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly)
Vapor Presure	1.66E-12mmHg at 25°C
Appearance	Crystalline Powder
Color	White
pKa	12.05±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.588
Physical and Chemical Properties	Pure white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.

Application	(2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionate methyl ester is an ester organic substance and can be used as a pharmaceutical intermediate.
Biological activity	Bz-RS-iSer(3-Ph)-OMe (compound 2) is a paclitaxel derivative that inhibits the HSV replication cycle under low cytotoxicity, blocks the mitosis of Vero cells, affects the size of M-MSV-induced tumors, and affects the immune response by inhibiting PHA-induced T lymphocyte proliferation.

Last Update：2024-04-09 15:16:49

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CAS: 32981-85-4
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Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052

Wechat: 15671228036

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paclitaxel side chain no.4

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